Alstonine, Flavopereirine, Sempervirine, Serpentine, Pao Pereira, Rauwolfia, Ginko biloba & the Work of Mirko Beljanski
For 40 years, the Yugoslavian molecular biologist, Mirko Beljanski PhD (1923–1998), in association with his wife and research associate, Monique, conducted research into the respective roles of DNA and RNA in the development and cure of cancer, first at the Pasteur Institute in France (1948–1978) and then at the Faculty of Pharmacy at Chatenay Malabry (1978–1988). During this time, he wrote 133 papers, published in both French and international journals.
Cancer is generally regarded as arising from damage to or mutations of the molecular structure of DNA. Beljanski’s primary thesis is that cancer is caused not only by DNA mutations but also by damage to the hydrogen bonds that hold the two strands of the DNA double helix together. Like a damaged zipper than is failing in places, allowing the two parts to separate, cancerous or pre-cancerous DNA has many broken or weakened hydrogen bonds. Once these bonds are broken over a particular area of the double helix, the DNA in that area is destabilized, and carcinogens are more readily able to infiltrate and cause the molecular damage that can lead to cancer. This explains, for example, why an excess of certain hormones such as estrogen and testosterone (and other steroids, too) is carcinogenic, although they do not appear to be the direct cause of mutations.
Among his other discoveries is that fragments of RNA (which he called Beljanski Leucocyte Restorers or BLBs) are capable of rapidly restoring the depletion of (red) blood platelets and (white) leucocytes brought about by radiation therapy and chemotherapy agents. BLBs selectively stimulate the normal replication of red and white blood cells in the bone marrow and spleen, without enhancing the proliferation of cancer cells. Beljanski reported that patients who received BLBs along with chemotherapy suffered few of the expected side effects, such as nausea and hair loss, and were able to continue with their normal daily lives.
Beljanski also developed what he called the ‘contest’ – a way of determining which kind of substances could destabilize DNA function, leading to cancerous cell proliferation, and, conversely, which kind of substances could repair or cause the programmed death (apoptosis) of damaged and cancer-forming DNA. Among such molecules, he discovered, are the naturally occurring plant alkaloids, also nine, flavopereirine, serpentine and sempervirine, which are able to distinguish between normal and cancer-forming DNA, either repairing the damaged DNA or causing the death of the malignant cells (apoptosis). Beljanski conducted many trials on the anti-cancer properties of these substances. He was able, for example, to cure an appreciable proportion of mice with lymphoma. Other in vitro studies showed that flavopereirine was active against a number of other cancer cell lines (brain, breast, ovarian, prostate, kidney, thyroid, pancreatic, colon, liver, skin), including those that were multidrug-resistant.
His research also showed that the flavanone, JO-1, which contains a large amount of naringin as well as some as yet unidentified substances, prevented the multiplication (in vitro) of human cancer cell lines (colon, ovary, breast, leukemia). Under the same experimental conditions, normal bone marrow cell multiplication was not affected. He also demonstrated that these substances also work in synergy with standard chemotherapy agents, providing better results than with the chemotherapy alone.
Dr Beljanski was forced to leave the Pasteur Institute when his innovative ideas came into conflict with the Institute’s new director. Underfunded, he continued his research and the publication of scientific papers, mostly in French. His wife, Monique, and daughter, Sylvia, now endeavor to bring the fruits of his research to a wider public. Sylvia Beljanski is president of Natural Source International Inc., in New York, the US company that now manufactures the Beljanski products.
Although he worked informally with many doctors in France and Belgium, Beljanski was largely ostracized by French oncologists. For a number of years prior to his death in 1998, he was persecuted as a charlatan, despite the commendations of many users of his products, including the French president, François Mitterand. In one instance, a journalist who had set out to expose Beljanski was not only unable to find any evidence of fraud, but ultimately became a grateful user of his products when he discovered that he himself had intestinal cancer. Beljanski’s work is the subject of a book, The Beljanski Anti-Cancer Remedies: Inside the Double Helix of DNA (2006).
The Beljanski products are now manufactured in the USA according to Beljanski’s methods. They have been shown to be totally non-toxic to animals and humans in the recommended doses:
|Pao V||An extract of the bark of the Amazonian tree, Pao Pereira (Geissospermum vellosii), contains the alkaloid flavopereirine (also called PB-100). Flavopereirine is a smaller molecule than also nine, and is able to cross the blood-brain barrier, making it useful in the treatment of brain tumors. Research studies, many being in vitro, have shown flavopereirine to be effective|